L. De Garavilla: search on Z-Library

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1

Selection of a 2-azabicyclo[2.2.2]octane-based α4β1 integrin antagonist as an inhaled anti-asthmatic agent

Edward C. Lawson, Rosemary J. Santulli, Alexey B. Dyatkin, Scott A. Ballentine, William M. Abraham, Sandra Rudman, Clive P. Page, Lawrence de Garavilla, Bruce P. Damiano, William A. Kinney, Bruce E. M

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 203 KB

english, 2006

2

Extended cleavage specificity of sheep mast cell protease-2: A classical chymase with preference to aromatic P1 substrate residues

Fu, Zhirong, Akula, Srinivas, Thorpe, Michael, Chahal, Gurdeep, de Garavilla, Lawrence, Kervinen, Jukka, Hellman, Lars

Journal:

Developmental & Comparative Immunology

Year:

2019

Language:

english

File:

PDF, 3.50 MB

english, 2019

3

Corrigendum to “Bridged bicyclic vasopressin receptor antagonists with V2-selective or dual V1a/V2 activity”: [Bioorg. Med. Chem. Lett. 12 (2002) 3081]

Alexey B. Dyatkin, William J. Hoekstra, Dennis J. Hlasta, Patricia Andrade-Gordon, Lawrence de Garavilla, Keith T. Demarest, Joseph W. Gunnet, William Hageman, Richard Look, Bruce E. Maryanoff

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 207 KB

english, 2004

4

Thrombin and trypsin directly activate vagal C-fibres in mouse lung via protease-activated receptor-1

Kevin Kwong, Christina Nassenstein, Lawrence De Garavilla, Sonya Meeker, Bradley J. Undem

Journal:

The Journal of Physiology

Year:

2010

Language:

english

File:

PDF, 243 KB

english, 2010

5

Potency variation of small-molecule chymase inhibitors across species

Jukka Kervinen, Carl Crysler, Shariff Bayoumy, Marta C. Abad, John Spurlino, Ingrid Deckman, Michael N. Greco, Bruce E. Maryanoff, Lawrence de Garavilla

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 359 KB

english, 2010

6

Cleaved secretory leucocyte protease inhibitor as a biomarker of chymase activity in allergic airway disease

S. M. Belkowski, J. D. Boot, M. A. Mascelli, Z. Diamant, L. De Garavilla, B. Hertzog, D. Polkovitch, M. Towers, A. Batheja, M. R. D'Andrea

Journal:

Clinical & Experimental Allergy

Year:

2009

Language:

english

File:

PDF, 355 KB

english, 2009

7

Antagonism of the Cardiodepressant Effects of Adenosine during Acute Hypoxia

Jennifer Cummings, Justin L. Kaplan, Erhe Gao, Dawn Clas, William C. Dalsey, Lawrence De Garavilla

Journal:

Academic Emergency Medicine

Year:

2000

Language:

english

File:

PDF, 93 KB

english, 2000

8

Zaprinast, but not dipyridamole, reverses hemodynamic tolerance to nitroglycerin in vivo

Lawrence De Garavilla, Edward D. Pagani, R.Allan Buchholz, Ronald Dundore, Donald C. Bode, Marlo L. Volberg, Keith N. Jackson, Phillip Pratt, Paul J. Silver

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 1014 KB

english, 1996

9

Nonpeptide Inhibitors of Cathepsin G: Optimization of a Novel β-Ketophosphonic Acid Lead by Structure-Based Drug Design

Greco, Michael N., Hawkins, Michael J., Powell, Eugene T., Almond,, Harold R., Corcoran, Thomas W., de Garavilla, Lawrence, Kauffman, Jack A., Recacha, Rosario, Chattopadhyay, Debashish, Andrade-Gordo

Journal:

Journal of the American Chemical Society

Year:

2002

Language:

english

File:

PDF, 105 KB

english, 2002

10

Extended Cleavage Specificities of Rabbit and Guinea Pig Mast Cell Chymases: Two Highly Specific Leu-Ases

Zhongwei, Yuan, Akula, Srinivas, Fu, Zhirong, de Garavilla, Lawrence, Kervinen, Jukka, Thorpe, Michael, Hellman, Lars

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 5.98 MB

english, 2019

11

Bridged bicyclic vasopressin receptor antagonists with V2-Selective or dual V1a/V2 activity

Alexey B Dyatkin, William J Hoekstra, Dennis J Hlasta, Patricia Andrade-Gordon, Lawrence de Garavilla, Keith T Demarest, Joseph W Gunnet, William Hageman, Richard Look, Bruce E Maryanoff

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 119 KB

english, 2002

12

Hypertonic Saline Treatment of Severe Hyperkalemia in Nonnephrectomized Dogs

Justin L. Kaplan, C. Andrew Eynon, William C. Dalsey, Leonard E. Braitman, Dawn Clas, Lawrence de Garavilla

Journal:

Academic Emergency Medicine

Year:

2000

Language:

english

File:

PDF, 119 KB

english, 2000

13

The role of the epithelium in chronic inflammatory airway disease

Paul L. Dudas, Lawrence de Garavilla, Lennart K.A. Lundblad, Darryl A. Knight

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2012

Language:

english

File:

PDF, 105 KB

english, 2012

14

Adenosine A1 Antagonism Attenuates Atropine-resistant Hypoxic Bradycardia in Rats

Justin L. Kaplan, Erhe Gao, Lawrence De Garavilla, Michelle Victain, Bohdan Minczak, William C. Dalsey

Journal:

Academic Emergency Medicine

Year:

2003

Language:

english

File:

PDF, 203 KB

english, 2003

15

Exercise in the Heat: Effects of an Adenosine Antagonist

Durkot, M. J., de Garavilla, L.

Journal:

International Journal of Sports Medicine

Year:

2000

Language:

english

File:

PDF, 120 KB

english, 2000

16

Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities

Thorpe, Michael, Fu, Zhirong, Chahal, Gurdeep, Akula, Srinivas, Kervinen, Jukka, de Garavilla, Lawrence, Hellman, Lars, Jeltsch, Albert

Journal:

Year:

2018

Language:

english

File:

PDF, 18.59 MB

english, 2018

17

Effect of nifedipine on core cooling in rats during tail cold water immersion

Michael J. Durkot, Lawrence de Garavilla

Journal:

Journal of Thermal Biology

Year:

2003

Language:

english

File:

PDF, 180 KB

english, 2003

18

CHARACTERIZATION OF RWJ-351647, A NOVEL NONPEPTIDE VASOPRESSIN V2 RECEPTOR ANTAGONIST

Joseph W Gunnet, Jay M Matthews, Bruce E Maryanoff, Lawrence De Garavilla, Patricia Andrade-Gordon, Bruce Damiano, William Hageman, Richard Look, Paul Stahle, Anthony J Streeter, Pamela G Wines, Keith

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2006

Language:

english

File:

PDF, 154 KB

english, 2006

19

Dextrose is absorbed by rectum in hypoglycemic rats

Douglas McGee, Andy Chen, Lawrence de Garavilla

Journal:

The Journal of Emergency Medicine

Year:

2003

Language:

english

File:

PDF, 114 KB

english, 2003

20

Highly Selective Cleavage of Cytokines and Chemokines by the Human Mast Cell Chymase and Neutrophil Cathepsin G

Fu, Zhirong, Thorpe, Michael, Alemayehu, Rahel, Roy, Ananya, Kervinen, Jukka, de Garavilla, Lawrence, Åbrink, Magnus, Hellman, Lars

Journal:

The Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 2.38 MB

english, 2017

21

Adenosine A1 Antagonism Attenuates β-adrenergic–resistant Sudden Hypoxic Cardiac Insufficiency

Erhe Gao, Justin L. Kaplan, Michelle S. Victain, William C. Dalsey, Lawrence De Garavilla

Journal:

Academic Emergency Medicine

Year:

2005

Language:

english

File:

PDF, 115 KB

english, 2005

22

Antiplatelet and Antithrombotic Activity of RWJ-53308, A Novel Orally Active Glycoprotein IIb/IIIa Antagonist

Bruce P Damiano, John A Mitchell, Edward Giardino, Thomas Corcoran, Barbara J Haertlein, Lawrence de Garavilla, Jack A Kauffman, William J Hoekstra, Bruce E Maryanoff, Patricia Andrade-Gordon

Journal:

Thrombosis Research

Year:

2001

Language:

english

File:

PDF, 616 KB

english, 2001

23

Potent nonpeptide vasopressin receptor antagonists based on oxazino- and thiazinobenzodiazepine templates

Jay M. Matthews, William J. Hoekstra, Alexey B. Dyatkin, Leonard R. Hecker, Dennis J. Hlasta, Brenda L. Poulter, Patricia Andrade-Gordon, Lawrence de Garavilla, Keith T. Demarest, Eric Ericson, Joseph

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 334 KB

english, 2004

24

Pharmacological characterization of RWJ-676070, a dual vasopressin V1A/V2 receptor antagonist

Joseph W. Gunnet, Pamela Wines, Min Xiang, Philip Rybczynski, Patricia Andrade-Gordon, Lawrence de Garavilla, Tom J. Parry, Wai-man Cheung, Lisa Minor, Keith T. Demarest, Bruce E. Maryanoff, Bruce P.

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 905 KB

english, 2008

25

Dual Inhibition of Cathepsin G and Chymase Is Effective in Animal Models of Pulmonary Inflammation

Maryanoff, Bruce E., de Garavilla, Lawrence, Greco, Michael N., Haertlein, Barbara J., Wells, Grace I., Andrade-Gordon, Patricia, Abraham, William M.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2010

Language:

english

File:

PDF, 170 KB

english, 2010

26

Cleaved SLPI, a novel biomarker of chymase activity

Belkowski, Stanley M., Masucci, John, Mahan, Andrew, Kervinen, Jukka, Olson, Matthew, de Garavilla, Lawrence, D'Andrea, Michael R.

Journal:

Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

27

Structural Basis for Elastolytic Substrate Specificity in Rodent -Chymases

Kervinen, J., Abad, M., Crysler, C., Kolpak, M., Mahan, A. D., Masucci, J. A., Bayoumy, S., Cummings, M. D., Yao, X., Olson, M., de Garavilla, L., Kuo, L., Deckman, I., Spurlino, J.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 1.20 MB

english, 2008

28

Cooperative antithrombotic effect from the simultaneous inhibition of thrombin and factor Xa

Giardino, Edward C, Haertlein, Barbara J, de Garavilla, Lawrence, Costanzo, Michael J, Damiano, Bruce P, Andrade-Gordon, Patricia, Maryanoff, Bruce E

Journal:

Blood Coagulation & Fibrinolysis

Year:

2010

Language:

english

File:

PDF, 401 KB

english, 2010

29

Variations on a theme of paracelsus: Bizarre developmental toxicity findings

Kathleen Van den Bulck, Graham P. Bailey, Lawrence De Garavilla, Roger Smith, Michael D’Andrea, Gennet Tegegne, Thanh Duong, Renee L. DesJarlais

Journal:

Reproductive Toxicology

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

30

OP0184 High Resolution Micro-Computerized Tomography Imaging as a Translational Tool to Quantitatively Assess Bone Damage in a Mouse Model of Collagen-Induced Arthritis in Mice: Disease Severity and Time-Course of Bone Changes

de Garavilla, L., Acton, P., Lubomirski, M., Malaviya, R., Shen, F., Shah, N., Vasquez, S., Yoder, V., Small, D., Weinstein, D., Kilgore, K.

Journal:

Annals of the Rheumatic Diseases

Year:

2013

Language:

english

File:

PDF, 298 KB

english, 2013

31

Novel low-molecular-weight superoxide dismutase mimic deferoxamine-manganese improves survival following hemorrhagic and endotoxic shock

Dr. Lawrence De Garavilla, Timothy Chermak, Heather L. Valentine, Robert C. Hanson

Journal:

Drug Development Research

Year:

1992

Language:

english

File:

PDF, 669 KB

english, 1992

32

Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives

Michael J. Costanzo, Stephen C. Yabut, Han-Cheng Zhang, Kimberley B. White, Lawrence de Garavilla, Yuanping Wang, Lisa K. Minor, Brett A. Tounge, Alexander N. Barnakov, Frank Lewandowski, Cynthia Mill

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 338 KB

english, 2008

33

THU0085 Effect of CSF-1R Kinase Inhibitor on FDG PET, MMP Optical, and Microct Imaging in a Rat SCW Model of Rheumatoid Arthritis: Use of Functional and Structural Imaging as Translation Tools

de Garavilla, L., Manthey, C., Yurkow, E., Zhou, Z., Cotto, C., Meegalla, S., Wilson, K., Wall, M., Chen, J., Ballentine, S., Illig, C., Player, M., Moore, B., Kilgore, K., Lubomirski, M., Acton, P.

Journal:

Annals of the Rheumatic Diseases

Year:

2013

Language:

english

File:

PDF, 285 KB

english, 2013

34

Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5

Thorpe, Michael, Fu, Zhirong, Albat, Emanuelle, Akula, Srinivas, de Garavilla, Lawrence, Kervinen, Jukka, Hellman, Lars, Jeltsch, Albert

Journal:

Year:

2018

Language:

english

File:

PDF, 6.81 MB

english, 2018

35

Corrigendum to “Aza-bicyclic amino acid sulfonamides as α4β1/α4β7 integrin antagonists”: [Bioorg. Med. Chem. Lett. 14 (2004) 591]

Alexey B Dyatkin, William J Hoekstra, William A Kinney, Maria Kontoyianni, Rosemary J Santulli, Edward S Kimball, M Carolyn Fisher, Stephen M Prouty, William M Abraham, Lawrence de Garavilla, Patricia

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 205 KB

english, 2004

36

In vitro characterization of a novel series of platelet-derived growth factor receptor tyrosine kinase inhibitors

David G. Sawutz, Donald C. Bode, G.Maurice Briggs, John R. Reid, Paul Canniff, Lisa Caldwell, Connie R. Faltynek, Deborah Miller, Joseph A. Dunn, Lawrence de Garavilla, Joseph W. Guiles, Carolyn Weige

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 1011 KB

english, 1996

37

Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism

Lawrence de Garavilla, Nathalie Vergnolle, Steven H Young, Helena Ennes, Martin Steinhoff, Valeria S Ossovskaya, Michael R D'Andrea, Emeran A Mayer, John L Wallace, Morley D Hollenberg, Patricia Andra

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 1.38 MB

english, 2001

38

Bridged Bicyclic Vasopressin Receptor Antagonists with V2-Selective or Dual V1a/V2 Activity.

Alexey B. Dyatkin, William J. Hoekstra, Dennis J. Hlasta, Patricia Andrade-Gordon, Lawrence de Garavilla, Keith T. Demarest, Joseph W. Gunnet, William Hageman, Richard Look, Bruce E. Maryanoff

Journal:

Year:

2003

File:

PDF, 204 KB

2003

39

Prediction of Hyperkalemia in Dogs from Electrocardiographic Parameters Using an Artificial Neural Network

Robert S. Porter, Justin Kaplan, Ning Zhao, Lawrence de Garavilla, C. Andrew Eynon, Fred G. Wenger, William C. Dalsey

Journal:

Academic Emergency Medicine

Year:

2001

Language:

english

File:

PDF, 58 KB

english, 2001

40

Adenosine A1 Receptor Antagonist Prolongs Survival in the Hypoxic Rat

Gao, Erhe, Kaplan, Justin L., Shi, Yaming, Victain, Michelle, Dalsey, William C., de Garavilla, Lawrence

Journal:

Journal of Cardiovascular Pharmacology

Year:

2001

Language:

english

File:

PDF, 679 KB

english, 2001

41

Use of Tube Condensation as an Indicator of Endotracheal Tube Placement

John J Kelly, C.Andrew Eynon, Justin L Kaplan, Lawrence de Garavilla, William C Dalsey

Journal:

Annals of Emergency Medicine

Year:

1998

Language:

english

File:

PDF, 53 KB

english, 1998

42

An experimental circulatory arrest model in the rat to evaluate calcium antagonists in cerebral resuscitation

De Garavilla, Lawrence, Babbs, Charles F., Tacker, Willis A.

Journal:

The American Journal of Emergency Medicine

Year:

1984

Language:

english

File:

PDF, 772 KB

english, 1984

43

Controlling the acute hemodynamic effects associated with IV administration of particulate drug dispersions in dogs

Lawrence de Garavilla, Nancy Peltier, Elaine Merisko-Liversidge

Journal:

Drug Development Research

Year:

1996

Language:

english

File:

PDF, 946 KB

english, 1996

44

Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonists

Jay M Matthews, Michael N Greco, Leonard R Hecker, William J Hoekstra, Patricia Andrade-Gordon, Lawrence de Garavilla, Keith T Demarest, Eric Ericson, Joseph W Gunnet, William Hageman, Richard Look, J

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 131 KB

english, 2003

45

Zaprinast but not dipyridamole reverses hemodynamic tolerance to nitroglycerin

Lawrence de Garavilla, Phillip F Pratt, Mario L Volberg, Glenn Van Aller, R Allan Buchholz, Edward D Pagani, Paul J Silver

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1992

Language:

english

File:

PDF, 117 KB

english, 1992

46

Cardiovascular activity of WIN 65579, a novel inhibitor of cyclic GMP phosphodiesterase 5

Paul J Silver, Edward D Pagani, Ronald L Dundore, Lawrence de Garavilla, D.Chris Bode, Edward R Bacon

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 128 KB

english, 1998

47

Structure–Function Analysis of Urotensin II and Its Use in the Construction of a Ligand–Receptor Working Model

William A. Kinney, Harold R. Almond, Jr., Jenson Qi, Charles E. Smith, Rosemary J. Santulli, Lawrence de Garavilla, Patricia Andrade-Gordon, Daniel S. Cho, Anita M. Everson, Mark A. Feinstein, Perry A

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 151 KB

english, 2002

48

Cardiovascular effects of adenosine and the adenosine A1 Receptor antagonist NPC 205 are altered with age in guinea pigs

Lawrence de Garavilla, Heather L. Valentine, Jan S. Schenden, William J. Kinnier, Robert C. Hanson

Journal:

Drug Development Research

Year:

1993

Language:

english

File:

PDF, 554 KB

english, 1993

49

Reversal or nitroglycerin tolerance by the cGMP phosphodiesterase inhibitor zaprinast

Paul J. Silver, Edward D. Pagani, Lawrence de Garavilla, Glenn S. VanAller, Marlo L. Volberg, Phillip F. Pratt, R.Allan Buchholz

Journal:

European Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 197 KB

english, 1991

50

A Novel, Potent Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase: MOLECULAR MECHANISMS AND ANTI-INFLAMMATORY ACTIVITY IN VIVO

de Garavilla, L., Greco, M. N., Sukumar, N., Chen, Z.-W., Pineda, A. O., Mathews, F. S., Di Cera, E., Giardino, E. C., Wells, G. I., Haertlein, B. J., Kauffman, J. A., Corcoran, T. W., Derian, C. K.,

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 777 KB

english, 2005

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